BDBM50243368 1-(3-carbamoyl-5-(4-(3-(dimethylamino)propoxy)phenyl)thiophen-2-yl)urea::CHEMBL452529

SMILES CN(C)CCCOc1ccc(cc1)-c1cc(C(N)=O)c(NC(N)=O)s1

InChI Key InChIKey=MKFBFGXYGIKOGL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243368   

TargetSerine/threonine-protein kinase Chk1(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50243368(1-(3-carbamoyl-5-(4-(3-(dimethylamino)propoxy)phen...)
Affinity DataIC50: 230nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed