BDBM50280737 CHEMBL4166974

SMILES Cc1ccc2c(c1)c(c[nH]2)CN3CCC(CC3)NC(=O)[C@H](Cc4c[nH]c5c4cccc5)N

InChI Key InChIKey=HAGXHOXTZOWANA-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280737   

TargetSon of sevenless homolog 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50280737(CHEMBL4166974)
Affinity DataEC50:  2.51E+4nMAssay Description:Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)