BDBM50284756 (R)-5-Methyl-3-((S)-9-oxo-1,8-diaza-tricyclo[10.6.1.0*13,18*]nonadeca-12(19),13(18),14,16-tetraen-10-ylcarbamoyl)-hexanoic acid::5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID::CHEMBL282146

SMILES CC(C)C[C@H](CC(O)=O)C(=O)N[C@H]1Cc2cn(CCCCCCNC1=O)c1ccccc21

InChI Key InChIKey=AKWKBACKRMYPRV-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50284756   

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  14nMAssay Description:Inhibition of human Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  25nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  115nMAssay Description:Inhibition of human neutrophil gelatinase, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  850nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284756(5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article