BDBM50328726 (2R,4R)-N1-(4-chlorophenyl)-N2-(3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl)-4-methoxypyrrolidine-1,2-dicarboxamide::(2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[3-FLUORO-2'-(METHYLSULFONYL)BIPHENYL-4-YL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE::4-Substituted Pyrrolidine Ring, 18::4-Substituted Pyrrolidine Ring, 19::CHEMBL1229814

SMILES CO[C@@H]1C[C@@H](N(C1)C(=O)Nc2ccc(cc2)Cl)C(=O)Nc3ccc(cc3F)c4ccccc4S(=O)(=O)C

InChI Key InChIKey=QBTQRXKLWHEJQY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328726   

TargetCoagulation factor X(Human)
Pfizer

LigandPNGBDBM50328726(CHEMBL1229814 | 4-Substituted Pyrrolidine Ring, 18...)
Affinity DataIC50: 0.160nMAssay Description:FXa inhibition were determined by using an inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

LigandPNGBDBM50328726(CHEMBL1229814 | 4-Substituted Pyrrolidine Ring, 18...)
Affinity DataIC50: 1.70nMAssay Description:FXa inhibition were determined by using an inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2011
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

LigandPNGBDBM50328726(CHEMBL1229814 | 4-Substituted Pyrrolidine Ring, 18...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed