BDBM50329059 CHEMBL1236772::GTC000121A::N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)pyrimidine-2,4-diamine::N^4^-1H-INDAZOL-4-YL-N^2^-[3-(METHYLSULFONYL)PHENYL]PYRIMIDINE-2,4-DIAMINE

SMILES CS(=O)(=O)c1cccc(c1)Nc2nccc(n2)Nc3cccc4c3cn[nH]4

InChI Key InChIKey=FIWCLCRWDUELGO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50329059   

LigandPNGBDBM50329059(N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 65.2nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R

LigandPNGBDBM50329059(N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 136nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R

LigandPNGBDBM50329059(N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 237nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R

LigandPNGBDBM50329059(N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 547nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R

TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329059(N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 61nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329059(N4-(1H-indazol-4-yl)-N2-(3-(methylsulfonyl)phenyl)...)
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed