BDBM50334352 4-(3-cyclopentylureido)benzenesulfonamide::4-[(cyclopentylcarbamoyl)amino]benzenesulfonamide::CHEMBL1615215

SMILES c1cc(ccc1NC(=O)NC2CCCC2)S(=O)(=O)N

InChI Key InChIKey=QRZYENXYGGOPSS-UHFFFAOYSA-N

Data  12 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50334352   

TargetCarbonic anhydrase 12(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  7nMAssay Description:Inhibition of human carbonic anhydrase 12 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  7nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 12 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of human carbonic anhydrase 9 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of tumor-associated human carbonic anhydrase 9 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  226nMAssay Description:Inhibition of human carbonic anhydrase 2 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  226nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  226nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  226nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  470nMAssay Description:Inhibition of human carbonic anhydrase 1 for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florida College of Medicine

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  470nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 min by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  509nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv1284 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50334352(4-(3-cyclopentylureido)benzenesulfonamide | 4-[(cy...)
Affinity DataKi:  733nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant beta-carbonic anhydrase Rv3273 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed