BDBM50338677 6-CHLORO-N-((3S)-2-OXO-1-{4-[(2S)-2-PYRROLIDINYL]PHENYL}-3-PYRROLIDINYL)-2-NAPHTHALENESULFONAMIDE::6-chloro-N-((S)-1-(2-fluoro-4-((S)-pyrrolidin-2-yl)phenyl)-2-oxopyrrolidin-3-yl)naphthalene-2-sulfonamide::CHEMBL1614818

SMILES c1cc(cc2c1cc(cc2)Cl)S(=O)(=O)N[C@H]3CCN(C3=O)c4ccc(cc4F)[C@@H]5CCCN5

InChI Key InChIKey=OKMBULRSJZKGQF-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338677   

TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50338677(6-CHLORO-N-((3S)-2-OXO-1-{4-[(2S)-2-PYRROLIDINYL]P...)
Affinity DataKi:  2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50338677(6-CHLORO-N-((3S)-2-OXO-1-{4-[(2S)-2-PYRROLIDINYL]P...)
Affinity DataKi:  4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)