BDBM50345231 5-bromo-1-benzofuran-2-carboxylic acid::5-bromobenzofuran-2-carboxylic acid::CHEMBL1738916

SMILES c1cc2c(cc1Br)cc(o2)C(=O)O

InChI Key InChIKey=QKUWZCOVKRUXKX-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345231   

TargetSerine/threonine-protein kinase pim-1(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345231(5-bromo-1-benzofuran-2-carboxylic acid | 5-bromobe...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345231(5-bromo-1-benzofuran-2-carboxylic acid | 5-bromobe...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human Pim-1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate preincubated for 15 mins prior substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)