BDBM50348880 CHEMBL1807446

SMILES Cc1ccc(cc1Nc2c3c(c(cn3ncn2)C(=O)c4ccccc4)C)C(=O)NC5CC5

InChI Key InChIKey=CQPNJQRTSADQCI-UHFFFAOYSA-N

Data  24 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50348880   

TargetMitogen-activated protein kinase 8(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 4nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 11(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 19nMAssay Description:Inhibition of p38betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 4nMAssay Description:Inhibition of human cloned GST-fused p38alpha expressed in Escherichia coli using myelin basic protein as substrate after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PKCzetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PKCdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of HER1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of AktMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 12(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of p38-gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of p38deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50348880(CHEMBL1807446)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed