BDBM50366804 CHEMBL4169491

SMILES c1ccc2c(c1)cc(n2c3cccc(c3)C(F)(F)F)C(=O)N

InChI Key InChIKey=IRJUBZXSBPCNAU-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50366804   

TargetGroup 10 secretory phospholipase A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366804(CHEMBL4169491)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGroup 10 secretory phospholipase A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366804(CHEMBL4169491)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)