BDBM50385082 CHEMBL2035633

SMILES CN1CCN(CC1)CC2=Nc3c4cc(ccc4oc3C(=O)N2)Br

InChI Key InChIKey=OOINHKLROPYETD-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50385082   

TargetSerine/threonine-protein kinase pim-1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50385082(CHEMBL2035633)
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-2(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50385082(CHEMBL2035633)
Affinity DataIC50: 197nMAssay Description:Inhibition of N-terminal His-tagged human PIM2 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50385082(CHEMBL2035633)
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal His-tagged human PIM3 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by luciferasse-luciferin-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed