BDBM50396262 CHEMBL2172322

SMILES C=CCNS(=O)(=O)c1cccc(c1)C(=O)Nc2nc3cc(ccc3n2C4CCC(CC4)CO)CN5CCCCC5

InChI Key InChIKey=LWJAHJMKAARBCO-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396262   

TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50396262(CHEMBL2172322)
Affinity DataIC50: 48nMAssay Description:Inhibition of ALK Tyr1604 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50396262(CHEMBL2172322)
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50396262(CHEMBL2172322)
Affinity DataIC50: 5.92E+3nMAssay Description:Inhibition of c-Met enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed