BDBM50398195 CHEMBL2177238

SMILES C[C@]1(C(=O)N(C(=O)N1C)c2ccc(c(c2)C(F)(F)F)C#N)c3ccc(cc3)O

InChI Key InChIKey=IHPVXUVRRPAUIQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398195   

TargetProgesterone receptor(Human)
Galapagos, Parc Biocitech

Curated by ChEMBL
LigandPNGBDBM50398195(CHEMBL2177238)
Affinity DataIC50: 8.80E+3nMAssay Description:Binding affinity to progesterone receptor by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Galapagos, Parc Biocitech

Curated by ChEMBL
LigandPNGBDBM50398195(CHEMBL2177238)
Affinity DataIC50: 9.60nMAssay Description:Binding affinity to androgen receptor by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Galapagos, Parc Biocitech

Curated by ChEMBL
LigandPNGBDBM50398195(CHEMBL2177238)
Affinity DataEC50:  0.900nMAssay Description:Modulation of Androgen receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)