BDBM50399646 CHEMBL2177668::PS210

SMILES c1ccc(cc1)[C@H](CC(=O)c2ccc(cc2)C(F)(F)F)C(C(=O)O)C(=O)O

InChI Key InChIKey=MLJPLHGJBUWCBA-UHFFFAOYSA-N

Data  1 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50399646   

TargetSerine/threonine-protein kinase PKH2 [1-944](Yeast)
Universit£Tsklinikum Frankfurt

LigandPNGBDBM50399646(CHEMBL2177668 | PS210)
Affinity DataEC50:  6.00E+4nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen Assay (Perkin Elmer) was performed according to the manufacturer's protocol in 384-well microtiter plates. Incubations were performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
Universit£Tsklinikum Frankfurt

LigandPNGBDBM50399646(CHEMBL2177668 | PS210)
Affinity DataIC50: 3.90E+4nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen Assay (Perkin Elmer) was performed according to the manufacturer's protocol in 384-well microtiter plates. Incubations were performe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target3-phosphoinositide-dependent protein kinase 1(Human)
Universit£Tsklinikum Frankfurt

LigandPNGBDBM50399646(CHEMBL2177668 | PS210)
Affinity DataEC50:  8.58E+4nMAssay Description:Increase in thermal stability of PDK1 by differential scanning fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)