BDBM50426461 CHEMBL2322677

SMILES c1cc2c(c[nH]c2nc1)c3cc(nc(c3)Cl)NC4CCCCC4

InChI Key InChIKey=JKTMEYXRCJFWAI-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426461   

TargetCell division cycle 7-related protein kinase(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50426461(CHEMBL2322677)Copy SMILESCopy InChI

Affinity DataKi:  0.900nMAssay Description:Inhibition of human Cdc7 using biotin-C6linker-TPSDSLIYDDGLS as substrate after 1 hrMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50426461(CHEMBL2322677)Copy SMILESCopy InChI

Affinity DataKi:  58nMAssay Description:Inhibition of human recombinant GSK3betaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
9/24/2013
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL