BDBM50433811 CHEMBL2382332

SMILES CC(C)c1ccc(cc1)N(C)c2cc3c(nc(nc3nc2)N)N

InChI Key InChIKey=CRSDIJKYSOUKQH-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433811   

TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50433811(CHEMBL2382332)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50433811(CHEMBL2382332)
Affinity DataKi:  11nMAssay Description:Inhibition of human DHFR using dihydrofolate as substrate after 180 secs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)