BDBM50439267 CHEMBL2419475

SMILES CCCCc1cc2c3ccccc3nc(c2o1)N

InChI Key InChIKey=TVEPYAGOSGVFCI-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439267   

TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50439267(CHEMBL2419475)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells co-transfected with MD2 and sAP assessed as induction of NF-kappaB activity by reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50439267(CHEMBL2419475)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at TLR8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)