BDBM50446019 CHEMBL3103347

SMILES c1cc(ccc1N2CCN(CC2)C(=O)N3CCOCC3)Cl

InChI Key InChIKey=KDSIRFZJOTZBPT-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50446019   

TargetAldo-keto reductase family 1 member C3(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446019(CHEMBL3103347)
Affinity DataIC50: 18nMAssay Description:Inhibition of AKR1C3 (unknown origin) expressed in human HCT116 cells assessed as formation of PR-104H from PR-104A preincubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C4(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446019(CHEMBL3103347)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant AKR1C4 (unknown origin) after 1 hr by competitive fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446019(CHEMBL3103347)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant AKR1C3 (unknown origin) after 1 hr by competitive fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446019(CHEMBL3103347)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) after 1 hr by competitive fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446019(CHEMBL3103347)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant AKR1C1 (unknown origin) after 1 hr by competitive fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)