BDBM50455900 CHEMBL4215676

SMILES c1c2c(cc3c1nc(s3)CCC(=O)O)sc(n2)CCC(=O)O

InChI Key InChIKey=RNLHVOCFLIRTNO-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455900   

TargetHistone deacetylase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50455900(CHEMBL4215676)
Affinity DataKd:  8.00E+3nMAssay Description:Binding affinity to biotinylated HDAC6 ZnF-UBD (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50455900(CHEMBL4215676)
Affinity DataIC50: 5.10E+3nMAssay Description:Displacement of N-terminal FITC-labeled RLRGG from N-terminal AviTag/C-terminal His6-tagged HDAC6 ZnF-UBD (unknown origin) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)