BDBM50464211 CHEMBL4243567

SMILES C[C@H](C1CC1)Nc2c3cccc(c3nc(n2)Nc4ccc(c(c4)Cl)F)C5=CCNCC5

InChI Key InChIKey=YQFXBUIYNRLMAO-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464211   

TargetSon of sevenless homolog 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50464211(CHEMBL4243567)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)