BDBM50465228 CHEMBL4287739

SMILES C[C@H](CC(=O)N1CCC(CC1)(CN2C=Nc3c(csc3C2=O)Br)O)c4ccccc4

InChI Key InChIKey=NRRXSEFLOFZNSO-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465228   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465228(CHEMBL4287739)
Affinity DataIC50: 300nMAssay Description:Inhibition of USP7 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465228(CHEMBL4287739)
Affinity DataIC50: 300nMAssay Description:Inhibition of human USP7 using Ub-Rho110 as substrate by fluorescence based SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)