BDBM50494296 CHEMBL3086685

SMILES c1ccc(cc1)C(=O)Nc2cc(ccc2F)Nc3ccc4c(c3)OCc5ccc(cc5C4=O)OCCN6CCOCC6

InChI Key InChIKey=OPUXVIDSMSFXIU-UHFFFAOYSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50494296   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50494296(CHEMBL3086685)
Affinity DataIC50: 1nMAssay Description:Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50494296(CHEMBL3086685)
Affinity DataKd:  17nMAssay Description:Binding affinity to P38alpha MAPK (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50494296(CHEMBL3086685)
Affinity DataIC50: 1nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)