BDBM50496328 CHEMBL3126187

SMILES c1ccc(cc1)[C@@](C2CCCC2)(C3CCN(CC3)CCCOc4ccc(cc4)C#N)O

InChI Key InChIKey=QBITUTDDFZQXDO-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496328   

TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50496328(CHEMBL3126187)
Affinity DataKd:  285nMAssay Description:Binding affinity to human menin by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50496328(CHEMBL3126187)
Affinity DataIC50: 270nMAssay Description:Inhibition of human His-tagged menin-biotinylated MLL (4 to 15) interaction after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)