BDBM50504041 CHEMBL4529787
SMILES CC1=CC[C@]2(C[C@@H]1O)[C@@H](CC[C@@H]2C(=O)O)C(C)C
InChI Key InChIKey=ZIOMQRRFPWLXDN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50504041
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of 11beta-HSD1 in human microsomes using [3H] cortisone as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
3D Structure (crystal)Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of 11beta-HSD2 (unknown origin) expressed in HEK293 cells using cortisone as substrate measured after 2 hrs in presence of NAD+ by HTRF as...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
The University of Tennessee Health Science Center
Curated by ChEMBL
The University of Tennessee Health Science Center
Curated by ChEMBL
Affinity DataKi: 620nMAssay Description:Inhibition of N-terminal MKHQHQHQHQHQHQQPL-tagged 11beta-HSD1 C272S mutant (unknown origin) expressed in Escherichia coli BL21 (DE3) using cortisol a...More data for this Ligand-Target Pair