BDBM50514885 CHEMBL4589592

SMILES C[C@H]1CCN(C1)S(=O)(=O)c2cc(ccc2Br)NC(=O)CN3C(=O)[C@@](NC3=O)(C)C4CC4

InChI Key InChIKey=XHAYAQCABOVSNX-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514885   

TargetChromatin remodeling regulator CECR2(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50514885(CHEMBL4589592)
Affinity DataIC50: 126nMAssay Description:Displacement of Alexa Fluor 647-labeled GSK tracer from FLAG-6His-Tev-fused CECR2 (424 to 543 residue) (unknown origin) measured after 15 mins by TR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50514885(CHEMBL4589592)
Affinity DataIC50: 100nMAssay Description:Displacement of Alexa Fluor 488-labeled ligand from FLAG-6His-Tev-fused ATAD2 (981 to 1121 residue) (unknown origin) measured after 30 mins by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50514885(CHEMBL4589592)
Affinity DataIC50: 5.01E+4nMAssay Description:Displacement of Alexa Fluor 647-labeled ligand from BRD4 BD1 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed