BDBM50536479 CHEMBL4068255

SMILES C[C@@H](c1cc2cccnc2cc1F)n1cnc2ncc(nc12)-c1cnn(C)c1

InChI Key InChIKey=SXWUXXWVCWEUTA-UHFFFAOYSA-N

Data  18 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50536479   

TargetEphrin type-A receptor 2(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human EPHA2More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
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TargetInsulin-like growth factor 1 receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetReceptor tyrosine-protein kinase erbB-4(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERBB4More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetMacrophage-stimulating protein receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human RONMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetEpidermal growth factor receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetTyrosine-protein kinase ABL1(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ABLMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetMast/stem cell growth factor receptor Kit(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human c-KitMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetHepatocyte growth factor receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataEC50:  1.5nMAssay Description:Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetEphrin type-B receptor 2(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human EPHB2More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetFibroblast growth factor receptor 1(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetProto-oncogene tyrosine-protein kinase Src(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human c- SRCMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetEpidermal growth factor receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human EGFR T790M mutantMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human RETMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
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TargetPlatelet-derived growth factor receptor alpha(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetVascular endothelial growth factor receptor 1(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human FLT1More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetALK tyrosine kinase receptor(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ALKMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetTyrosine-protein kinase receptor UFO(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human AXLMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetPlatelet-derived growth factor receptor beta(Human)
Shanghai Pharmaceuticals Holding

Curated by ChEMBL

LigandBDBM50536479(CHEMBL4068255)Copy SMILESCopy InChI

Affinity DataIC50: 2.62E+4nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/2/2021
Entry Details Article
Copy Entry DOIPubMed
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