BDBM50538235 CHEMBL4632369

SMILES OC(=O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2OCCc2c1

InChI Key InChIKey=LOEBSRSQBHSNFT-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50538235   

TargetFatty acid-binding protein, adipocyte(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50538235(CHEMBL4632369)
Affinity DataKd:  37nMAssay Description:Binding affinity at recombinant human 6His-tagged FABP4 expressed in Escherichia coli BL21 DE3 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50538235(CHEMBL4632369)
Affinity DataIC50: 37nMAssay Description:Inhibition of FABP4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetFatty acid-binding protein, adipocyte(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50538235(CHEMBL4632369)
Affinity DataKi:  340nMAssay Description:Displacement of 1,8-ANS from FABP4 (unknown origin) assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetFatty acid-binding protein 5(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50538235(CHEMBL4632369)
Affinity DataKi:  820nMAssay Description:Displacement of 1,8-ANS from recombinant human 6His-tagged FABP5 expressed in Escherichia coli BL21 DE3 incubated for 15 mins followed by 1,8-ANS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetFatty acid-binding protein, heart(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50538235(CHEMBL4632369)
Affinity DataKi:  920nMAssay Description:Displacement of 1,8-ANS from FABP3 (unknown origin) assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetFatty acid-binding protein, heart(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50538235(CHEMBL4632369)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of 1,8-ANS from recombinant human 6His-tagged FABP3 expressed in Escherichia coli BL21 DE3 incubated for 15 mins followed by 1,8-ANS add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed