BDBM50541856 CHEMBL4635926

SMILES CC(C)(C)c1cc(n(n1)C)C(=O)N2CCC(CC2)C[C@@H](C(=O)NC)NC(=O)[C@@H]3CCCC(=O)N3

InChI Key InChIKey=SLKUTPSFHQUWLD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50541856   

TargetN-alpha-acetyltransferase 50(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50541856(CHEMBL4635926)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of wild type human Naa50 (1852 to 2082 residues) expressed in Escherichia coli BL21(DE3) cells using MLGPEGGEGK peptide as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-alpha-acetyltransferase 50(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50541856(CHEMBL4635926)
Affinity DataKd:  1.01E+3nMAssay Description:Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in presence of acetyl CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)