BDBM50542657 Jnj-53718678::Rilematovir

SMILES CS(=O)(=O)CCCn1c2ccc(cc2cc1CN3c4cnccc4N(C3=O)CC(F)(F)F)Cl

InChI Key InChIKey=GTQTUABHRCWVLL-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50542657   

TargetFusion glycoprotein F0(Human respiratory syncytial virus)
Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50542657(Rilematovir | Jnj-53718678)
Affinity DataEC50:  0.501nMAssay Description:Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)