BDBM50554401 CHEMBL4778578

SMILES Cc1cn(c2c1c(cc(n2)C(=O)N)Cl)[C@@H](C)[C@@]3(CCNC3)F

InChI Key InChIKey=HDYFVAJZXGMYBL-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554401   

TargetSerine/threonine-protein kinase pim-1(Human)
Sanofi

Curated by ChEMBL

LigandBDBM50554401(CHEMBL4778578)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetSerine/threonine-protein kinase pim-2(Human)
Sanofi

Curated by ChEMBL

LigandBDBM50554401(CHEMBL4778578)Copy SMILESCopy InChI

Affinity DataIC50: 6nMAssay Description:Inhibition of PIM2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sanofi

Curated by ChEMBL

LigandBDBM50554401(CHEMBL4778578)Copy SMILESCopy InChI

Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL