BDBM50567586 CHEMBL4867215

SMILES c1ccc(cc1)CCC(=O)N2CCC(CC2)(CN3C=Nc4cc(ccc4C3=O)Cl)O

InChI Key InChIKey=CITWIBXKKHFDFM-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50567586   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50567586(CHEMBL4867215)
Affinity DataIC50: 193nMAssay Description:Inhibition of full length His-tagged human recombinant USP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50567586(CHEMBL4867215)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human USP7 using Ub-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50567586(CHEMBL4867215)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of recombinant USP7 catalytic domain (unknown origin) using UbA10 as substrate incubated with substrate for 75 mins followed by compound a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)