BDBM50568434 CHEMBL4849950

SMILES c1ccc2c(c1)C(=O)c3cc(cc(c3C2=O)Cl)C(=O)O

InChI Key InChIKey=WRJVLGUSGCVLDE-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50568434   

TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50568434(CHEMBL4849950)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)