BDBM50580509 CHEMBL5083918::US20240122876, Example 3

SMILES CCCC(CCC)COc1cc(ccc1F)[C@@H](CCN)O

InChI Key InChIKey=WDYVEMOTVIKKNU-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50580509   

TargetRetinoid isomerohydrolase(Bovine)
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580509(CHEMBL5083918 | US20240122876, Example 3)
Affinity DataIC50: 50nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoid isomerohydrolase/Retinaldehyde-binding protein 1(Human)
Case Western Reserve University

US Patent
LigandPNGBDBM50580509(CHEMBL5083918 | US20240122876, Example 3)
Affinity DataIC50: 50nMAssay Description:Primary amine listed in Table 2 in DMF (1 μL) was added into a suspension containing 300 μg of RPE microsomal proteins, 1% bovine serum alb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)