BDBM50581216 CHEMBL5081135

SMILES Cn1c2c(c(c1Br)C#N)c(ncn2)N

InChI Key InChIKey=IUMDMPJAQOGMFA-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50581216   

TargetSerine/threonine-protein kinase PAK 4(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50581216(CHEMBL5081135)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PAK4 (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581216(CHEMBL5081135)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) assessed as accumulation of ADP by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50581216(CHEMBL5081135)
Affinity DataKi:  6.40E+3nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)