BDBM50589394 CHEMBL4797564

SMILES CNc1nc2c(c(c[nH]2)c3ccc4c(c3)cccn4)c(n1)NCc5ncccn5

InChI Key InChIKey=PMWVYONICYRLNY-UHFFFAOYSA-N

Data  4 IC50  5 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50589394   

TargetDual specificity protein kinase CLK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataKd:  0.0960nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK1(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataKd:  4.80nMAssay Description:Binding affinity to CLK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataKd:  0.0960nMAssay Description:Binding affinity to CLK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK3(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataKd:  6.5nMAssay Description:Binding affinity to CLK3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataKd:  0.610nMAssay Description:Binding affinity to CLK4 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetDual specificity protein kinase CLK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataIC50: 0.0960nMAssay Description:Inhibition of human CLK2 administered orallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK1(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human CLK1 administered orallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK3(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human CLK3 administered orallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
University of Canterbury

Curated by ChEMBL
LigandPNGBDBM50589394(CHEMBL4797564)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of human CLK4 administered orallyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed