BDBM50589971 CHEMBL5187038

SMILES CC(C)C[C@H](C(=O)NCCn1cc(nn1)COc2ccccc2NC(=O)C)C(=O)NO

InChI Key InChIKey=OJABORXYWINGBT-UHFFFAOYSA-N

Data  4 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50589971   

TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetStromelysin-1(Human)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataKi:  100nMAssay Description:Inhibition of Bacillus cereus ATCC 14579 collagenase unit of ColQ1 assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCollagenase ColA(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of Bacillus cereus ATCC 14579 collagenase unit of ColA assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataKi:  1.16E+4nMAssay Description:Inhibition of Clostridium histolyticum peptidase unit of ColH assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCollagenase ColG(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of Clostridium histolyticum collagenase unit of ColG assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)