BDBM50593995 CHEMBL5185276

SMILES COc1cc(ccc1C(=O)N)OCC2CCCCC2

InChI Key InChIKey=AELPJNFNRYUNNH-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50593995   

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593995(CHEMBL5185276)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human PARP-10 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593995(CHEMBL5185276)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human N-terminal 6His-tagged PARP15 (460 to 656 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593995(CHEMBL5185276)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PARP14 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593995(CHEMBL5185276)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PARP2 using NAD+ as substrate incubated for 10 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50593995(CHEMBL5185276)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal 6His-tagged TNKS2 (1030 to 1317 residues) expressed in Escherichia coli Rosetta2 (DE3) cells using NAD+ as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed