BDBM50601768 CHEMBL5193246

SMILES Cc1cnc(n1C)N2CCN(CC2)CCCC3=Nc4c(cccc4Cl)C(=O)N3

InChI Key InChIKey=HVYNZDGGVRBTFE-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50601768   

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50601768(CHEMBL5193246)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant N-terminal 6His-6Lys-TEV tagged PARP1 full length expressed in pFastBac expression system incubated for 4 hrs by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50601768(CHEMBL5193246)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant N-terminal Avi-6His-TEV tagged PARP2 full length expressed in pFastBac expression system incubated for 4 hrs by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50601768(CHEMBL5193246)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed