BDBM50604907 CHEMBL5198222

SMILES CC(C)(C)c1ccccc1OCC(=O)Nc2ccc(cc2)O

InChI Key InChIKey=RUNXUUCDTNJFME-UHFFFAOYSA-N

Data  1 Kd  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50604907   

TargetNicotinamide phosphoribosyltransferase(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50604907(CHEMBL5198222)
Affinity DataKd:  379nMAssay Description:Binding affinity to recombinant NAMPT (unknown origin) assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50604907(CHEMBL5198222)
Affinity DataEC50:  5.70E+3nMAssay Description:Binding affinity to recombinant NAMPT (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
School of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50604907(CHEMBL5198222)
Affinity DataEC50:  6.00E+3nMAssay Description:Activation of NAMPT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)