BDBM50605594 CHEMBL5186374

SMILES c1cc2c(cc1C#N)OC[C@H](S2)C3=CNC(=O)C(=O)N3

InChI Key InChIKey=GRRZGHVZXKQFHU-UHFFFAOYSA-N

Data  1 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50605594   

TargetD-amino-acid oxidase(Human)
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605594(CHEMBL5186374)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full length human DAO preincubated with compound for 20 mins measured after 4 hrs by Amplex red and horseradish peroxidase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD-amino-acid oxidase(Human)
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605594(CHEMBL5186374)
Affinity DataEC50:  630nMAssay Description:Inhibition of full length human DAO transfected in CHO-K1 cells incubated for 30 mins by Amplex red and horseradish peroxidase based fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD-amino-acid oxidase(Mouse)
Schr£Dinger

Curated by ChEMBL
LigandPNGBDBM50605594(CHEMBL5186374)
Affinity DataEC50:  780nMAssay Description:Inhibition of full length mouse DAO transfected with CHO-K1 cells incubated for 30 mins by Amplex red and horseradish peroxidase based fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed