BDBM50605648 CHEMBL5193673

SMILES COc1c2cc(ccc2c(c(n1)C(=O)NCC(=O)O)O)Oc3ccc(cc3)Cc4ccccc4

InChI Key InChIKey=DFTJBCOEWZOUPK-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605648   

TargetThyroid hormone receptor alpha(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50605648(CHEMBL5193673)
Affinity DataEC50:  53nMAssay Description:Agonist activity at wild type human TR alpha LBD expressed in Escherichia coli BL21 (DE3) assessed as induction of N-terminal biotinylated coactivato...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetThyroid hormone receptor beta(Human)
Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL
LigandPNGBDBM50605648(CHEMBL5193673)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human TR beta LBD (202 to 461 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as induction of N-terminal biotin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)