BDBM50606768 CHEMBL5220579

SMILES c1ccc2c(c1)CN(C2)C(=O)c3ccc(c(c3)Sc4ccc5c(c4)OCCO5)O

InChI Key InChIKey=GNTZGEZCMHJEGG-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50606768   

TargetHeat shock protein HSP 90-alpha(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50606768(CHEMBL5220579)
Affinity DataKd:  520nMAssay Description:Inhibition of human recombinant Hsp90alpha (1 to 223 residues) expressed in Escherichia coli BL21(DE3) incubated for 24 hrs by fluorescence polarizat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-beta(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50606768(CHEMBL5220579)
Affinity DataKd:  2.77E+4nMAssay Description:Inhibition of human recombinant Hsp90beta expressed in Escherichia coli BL21(DE3) incubated for 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed