BDBM50607287 CHEMBL5219727

SMILES COc1cc(c(cc1N2C(=O)C=C(NC2=O)C(F)(F)F)Cl)OC

InChI Key InChIKey=GGXGVBQCYFQKID-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607287   

LigandPNGBDBM50607287(CHEMBL5219727)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50607287(CHEMBL5219727)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed