BDBM50607320 CHEMBL5220089

SMILES Cc1cc(c2cc(ccc2n1)F)O

InChI Key InChIKey=BKXCHVFCJZJATJ-UHFFFAOYSA-N

Data  1 KI  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607320   

TargetKelch-like ECH-associated protein 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50607320(CHEMBL5220089)
Affinity DataKd:  1.80E+6nMAssay Description:Binding affinity to Keap1 kelch domain (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetKelch-like ECH-associated protein 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50607320(CHEMBL5220089)
Affinity DataKi:  2.60E+6nMAssay Description:Inhibition of recombinant human His-tagged Keap1 kelch domain (321 to 609 residues) expressed in Escherichia coli BL21(DE3) cells to Cy5-Nrf2 (unknow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)