BDBM50609301 CHEMBL4559961

SMILES CNCCN1CCC(CC1)c2cc(ccn2)CN(C)C(=O)c3cccc(c3)Oc4ccccc4

InChI Key InChIKey=VUIITYLFSAXKIQ-UHFFFAOYSA-N

Data  8 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50609301   

TargetHistone-arginine methyltransferase CARM1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609301(CHEMBL4559961)
Affinity DataIC50: 10nMAssay Description:Inhibition of FLAG-tagged CARM1 (unknown origin) (2 to 585 residues) using biotin-aminohexanoate-PRKQLATKAARMeKSAP-amide peptide as substrate preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609301(CHEMBL4559961)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609301(CHEMBL4559961)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein arginine N-methyltransferase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609301(CHEMBL4559961)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609301(CHEMBL4559961)
Affinity DataIC50: 340nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609301(CHEMBL4559961)
Affinity DataIC50: 43nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609301(CHEMBL4559961)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-arginine methyltransferase CARM1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50609301(CHEMBL4559961)
Affinity DataIC50: 181nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)