BDBM50610147 CHEMBL5289955
SMILES c1ccc(cc1)CNC(=O)c2cc(c(c(c2)Cl)Cl)C(=O)Nc3ccccc3
InChI Key InChIKey=JMJCTRILCXRIOZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50610147
TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard
Curated by ChEMBL
Institute of Mit and Harvard
Curated by ChEMBL
Affinity DataEC50: 3.40nMAssay Description:Inverse agonist activity at GST tagged human PPARgamma LBD (231 to 505 residues) expressed in Escherichia coli BL21(DE3) assessed as recruitment of f...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
Institute of Mit and Harvard
Curated by ChEMBL
Institute of Mit and Harvard
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inverse agonist activity at human PPARgamma in human RT112/84 transfected with NLuc-fused FABP4 assessed as reduction in PPARgamma transactivation in...More data for this Ligand-Target Pair