BDBM616156 (R)-2-(3-methyl-2,6-dioxopiperidin-3-yl)- 1,3-dioxoisoindoline-5-carboxylic acid::US20230271966, Compound 12

SMILES C[C@]1(CCC(=O)NC1=O)N2C(=O)c3ccc(cc3C2=O)C(=O)O

InChI Key InChIKey=VWVJRXADTDRXRW-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616156   

TargetEKC/KEOPS complex subunit TP53RK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616156(US20230271966, Compound 12 | (R)-2-(3-methyl-2,6-d...)
Affinity DataKd:  280nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616156(US20230271966, Compound 12 | (R)-2-(3-methyl-2,6-d...)
Affinity DataKd: >1.00E+6nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent