BDBM7762 N-Methyl-4-{[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-methyl]amino}benzenesulfonamide::N-methyl-4-({[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}amino)benzene-1-sulfonamide::Oxindole-Based Inhibitor 98

SMILES CNS(=O)(=O)c1ccc(cc1)N=CC1C(=O)Nc2ccccc12

InChI Key InChIKey=XTPZAFMBWDNWIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7762   

LigandPNGBDBM7762(N-Methyl-4-{[(2-oxo-1,2-dihydro-3H-indol-3-ylidene...)
Affinity DataIC50: 2.90E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM7762(N-Methyl-4-{[(2-oxo-1,2-dihydro-3H-indol-3-ylidene...)
Affinity DataIC50: 560nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed