Compile Data Set for Download or QSAR
Report error Found 93 Enz. Inhib. hit(s) with Target = '4,4'-diapophytoene synthase'
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50031845((4-Biphenyl-4-yl-1-phosphono-butyl)-phosphonic aci...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of Staphylococcus aureus CrtMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292847(4-[4-(4-Trifluoromethylphenyl)phenyl)]butyldiphosp...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292846(4-(4-Biphenyl)butyldiphosphonic Acid Tetrapotassiu...)
Affinity DataKi:  1nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50049236(Tripotassium salt of 4-(3-Phenoxy-phenyl)-1-phosph...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of Staphylococcus aureus CrtMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50049236(Tripotassium salt of 4-(3-Phenoxy-phenyl)-1-phosph...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 histidine-tagged full length CrtM expressed in Escherichia coli BL21(DE3) cells assessed as decrease i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2019
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50049222(1-Phosphono-4-[3-(4-propylphenoxy)phenyl]butylsulf...)
Affinity DataKi:  5nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292848(1-Phosphono-4-[3-(4-fluorophenoxy)phenyl]butylsulf...)
Affinity DataKi:  5nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50049231(CHEMBL347175 | CHEMBL513790 | Trisodium salt of 4-...)
Affinity DataKi:  6nMAssay Description:Inhibition of Staphylococcus aureus CrtMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268680(N-3-(3-phenoxyphenyl)propylphosphonoacetamide | CH...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268509(N-[3-(3-(3,4-Dichlorophenoxy)phenyl)propyl]phospho...)
Affinity DataKi:  30nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268510(N-[3-(3-Phenoxyphenyl)propyl]phosphonoacetamide Di...)
Affinity DataKi:  40nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268511(N-[3-(3-(4-Chlorophenoxy)phenyl)propyl]phosphonoac...)
Affinity DataKi:  70nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50049236(Tripotassium salt of 4-(3-Phenoxy-phenyl)-1-phosph...)
Affinity DataIC50: 83nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 full length His-tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells assesse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50049236(Tripotassium salt of 4-(3-Phenoxy-phenyl)-1-phosph...)
Affinity DataIC50: 110nMAssay Description:Inhibition of CrtM in Staphylococcus aureus assessed as reduction in staphyloxanthin levels after 72 hrs by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2019
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50626064(CHEMBL5402466)
Affinity DataKi:  135nMAssay Description:Inhibition of Staphylococcus aureus CrtMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292847(4-[4-(4-Trifluoromethylphenyl)phenyl)]butyldiphosp...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268512(3-(3-Phenoxyphenyl)propylphosphinylmethylphosphoni...)
Affinity DataKi:  220nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50388903(CHEMBL2063253)
Affinity DataKi:  250nMAssay Description:Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268563(N-Hydroxy-N-[3-(3-phenoxyphenyl)propyl]phosphonoac...)
Affinity DataKi:  320nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268562(N-Hydroxy-N-[3-(3-(3,4-dichlorophenoxy)phenyl)prop...)
Affinity DataKi:  320nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50388398(SQ-109 | CHEMBL561057)
Affinity DataKi:  360nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 dehydrosqualene synthase expressed in Escherichia coli BL21(DE3) after 30 mins by spectrophotometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50388906(CHEMBL2063256)
Affinity DataKi:  450nMAssay Description:Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292846(4-(4-Biphenyl)butyldiphosphonic Acid Tetrapotassiu...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268565(N-[3-(3-Phenoxyphenyl)propyl]sulfoacetamide | CHEM...)
Affinity DataKi:  810nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268564(N-[3-(4-Biphenyl)propyl]phosphonoacetamide | CHEMB...)
Affinity DataKi:  810nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268566(N-Methyl-N-[3-(3-phenoxyphenyl)propyl]phosphonoace...)
Affinity DataKi:  910nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268625(N-[3-(3-Phenoxyphenyl)propyl]phosphonodimethylacet...)
Affinity DataKi:  960nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50460685(CHEMBL4227773)
Affinity DataKi:  1.26E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292876((1S)-1-Phosphono-4-(3-phenoxyphenyl)butylsulfonic ...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50388397(CHEMBL39581)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 dehydrosqualene synthase expressed in Escherichia coli BL21(DE3) after 30 mins by spectrophotometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268626(N-[2-(3-Phenoxyphenyl)ethyl]phosphonoacetamide Dip...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292854(1-Phosphono-4-[3-(3,4-difluorophenoxy)phenyl]butyl...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292849(1-Phosphono-4-[3-(4-fluorophenoxy)-6-fluoro-phenyl...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292852(1-Phosphono-4-[3-(benzofuran-5-yloxy)phenyl]butyls...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50049222(1-Phosphono-4-[3-(4-propylphenoxy)phenyl]butylsulf...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292864(1-Phosphono-4-[3-(3-fluorophenoxy)phenyl]butylsulf...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292853(1-Phosphono-4-[3-(3,4-dichlorophenoxy)phenyl]butyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292848(1-Phosphono-4-[3-(4-fluorophenoxy)phenyl]butylsulf...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292860(1-Phosphono-4-[3-(4-chlorophenoxy)phenyl]butylsulf...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50388903(CHEMBL2063253)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Staphylococcus aureus isolate WT CrtM-mediated staphyloxanthin synthesis after 72 hrs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268627(N-Hydroxy-2-phosphono-5-(3-phenoxyphenyl)pentamide...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292851(1-Phosphono-4-[3-(3,5-difluorophenoxy)phenyl]butyl...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50460683(CHEMBL4227441)
Affinity DataKi:  5.19E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268628(N-[4-(3-Phenoxyphenyl)butyl]phosphonoacetamide Dip...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292875(4-(4-Biphenyl)butyldiphosphonic Acid tripotassium ...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50268629(3-(3-Phenoxyphenyl)propyl Phosphonoacetate Dipotas...)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of Staphylococcus aureus histidine tagged dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292866(1-Phosphono-4-(4-phenoxyphenyl)butylsulfonic Acid ...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292850(1-Phosphono-4-[3-(3,5-dichlorophenoxy)phenyl]butyl...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50460686(CHEMBL4228799)
Affinity DataKi:  6.89E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50292863(1-Phosphono-4-[3-(2-fluorophenoxy)phenyl]butylsulf...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of Staphylococcus aureus dehydrosqualene synthase expressed in Escherichia coli BL21 (DE3) cells by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
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