Compile Data Set for Download or QSAR
Report error Found 2570 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein'
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50195684(1-[4-(3-fluoropropoxy)-3-methoxyphenyl]-5-hydroxy-...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)
Affinity DataIC50: 0.100nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50101410((trans,trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4...)
Affinity DataKi:  0.110nMAssay Description:Inhibitory activity against binding of [125I]IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50101411(5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...)
Affinity DataKi:  0.130nMAssay Description:Inhibitory activity against binding of [125I]IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100131(5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...)
Affinity DataKi:  0.140nMAssay Description:Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM41537(US8865911, 114 | US10231967, Example 114 | US99189...)
Affinity DataIC50: 0.140nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100131(5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...)
Affinity DataKi:  0.140nMAssay Description:Inhibitory activity against binding of [125I]IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100131(5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100135(5-[2-{4-[2-(3-carboxy-4-methoxyphenyl)-(E)-1-ethen...)
Affinity DataKi:  0.170nMAssay Description:Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100135(5-[2-{4-[2-(3-carboxy-4-methoxyphenyl)-(E)-1-ethen...)
Affinity DataKi:  0.170nMAssay Description:Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM369585(US10231967, Example 94-Isomer-1)
Affinity DataIC50: 0.170nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50101413(5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...)
Affinity DataKi:  0.190nMAssay Description:Inhibitory activity against binding of [125I]IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50483880(CHEMBL1774642)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50067040(CHEMBL116438 | 1,7-bis(4-hydroxy-3-methoxyphenyl)1...)
Affinity DataKi:  0.208nMAssay Description:Displacement of [125I]IMSB from beta amyloid protein 40More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481603(CHEMBL607562)
Affinity DataKd:  0.210nMAssay Description:Displacement of [125I-N-Methyl-4-(4-bromoanilino)phthalimide from beta-amyloid plaques isolated from Alzheimer's disease patient brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393100(CHEMBL2152915 | US10231967, Example 125 | US991898...)
Affinity DataIC50: 0.260nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136856(US8865911, 92 Isomer 2 | US10231967, Example 92-Is...)
Affinity DataIC50: 0.270nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50101412(5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...)
Affinity DataKi:  0.270nMAssay Description:Inhibitory activity against binding of [125I]IMSB to amyloid beta in brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)
Affinity DataIC50: 0.280nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50220297(1-((2R,6S)-1-(4-chlorophenylsulfonyl)-6-(3,5-diflu...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane A-beta-40 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50483881(CHEMBL1774643)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393099(CHEMBL2152914 | US10231967, Example 122 | US991898...)
Affinity DataIC50: 0.300nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393102(US8865911, 20t | US8865911, 20t Isomer 1 | US88659...)
Affinity DataIC50: 0.360nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM369555(US10231967, Example 68-Isomer-1)
Affinity DataIC50: 0.380nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50100131(5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...)
Affinity DataKi:  0.400nMAssay Description:Inhibition constant of compound on ligand binding to aggregates of Amyloid beta was measured by comparing with [125I]-IMSBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393100(CHEMBL2152915 | US10231967, Example 125 | US991898...)
Affinity DataIC50: 0.5nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136858(US8865911, 94 Isomer 2 | US8865911, 94 Isomer 1 | ...)
Affinity DataIC50: 0.560nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393102(US8865911, 20t | US8865911, 20t Isomer 1 | US88659...)
Affinity DataIC50: 0.560nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50497728(CHEMBL3314344)
Affinity DataKd:  0.560nMAssay Description:Binding affinity to amyloid beta42 (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136739(US8865911, 20e | US10231967, Example 119 | US99189...)
Affinity DataIC50: 0.570nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136863(US8865911, 100 | US10231967, Example 100 | US99189...)
Affinity DataIC50: 0.590nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136761(US8865911, 20u | US9000182, 10 | US10231967, Examp...)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at -140 C. at a concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2015
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136854(US8865911, 91 | US10231967, Example 91 | US9918985...)
Affinity DataIC50: 0.620nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393100(CHEMBL2152915 | US10231967, Example 125 | US991898...)
Affinity DataIC50: 0.630nMAssay Description:The β-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human β-Secretase (AA 1-AA 460) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136761(US8865911, 20u | US9000182, 10 | US10231967, Examp...)
Affinity DataIC50: 0.630nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136739(US8865911, 20e | US10231967, Example 119 | US99189...)
Affinity DataIC50: 0.670nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM155101(US9000182, 11, isomer 1)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at -140 C. at a concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2015
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481120(Flutemetamol | [3H]-Flutemetamol)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human amyloid beta plaqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM369585(US10231967, Example 94-Isomer-1)
Affinity DataIC50: 0.700nMAssay Description:The β-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human β-Secretase (AA 1-AA 460) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM369525(US10231967, Example 48-Isomer-1 | US9918985, Examp...)
Affinity DataIC50: 0.700nMAssay Description:The β-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human β-Secretase (AA 1-AA 460) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM155100(US9000182, 9, isomer 1)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at -140 C. at a concent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2015
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50185948(5-hydroxy-2-(4-methylaminophenyl)benzofuran | CHEM...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [125I]IMPY from beta amyloid in human corpse AD brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393100(CHEMBL2152915 | US10231967, Example 125 | US991898...)
Affinity DataIC50: 0.720nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136863(US8865911, 100 | US10231967, Example 100 | US99189...)
Affinity DataIC50: 0.720nMAssay Description:The β-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human β-Secretase (AA 1-AA 460) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393104(CHEMBL2152918 | US10231967, Example 20aa | US99189...)
Affinity DataIC50: 0.720nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481120(Flutemetamol | [3H]-Flutemetamol)
Affinity DataKi:  0.740nMAssay Description:Displacement of [18F]-amyvid from amyloid-beta aggregates in alzheimer's disease patient brain homogenates after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50481120(Flutemetamol | [3H]-Flutemetamol)
Affinity DataKi:  0.740nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brain by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50393106(CHEMBL2152920 | US10231967, Example 72 | US9918985...)
Affinity DataIC50: 0.760nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136736(US8865911, 20b | US10231967, Example 20b | US99189...)
Affinity DataIC50: 0.780nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Sungkyunkwan University School of Medicine

Curated by ChEMBL
LigandPNGBDBM136848(US8865911, 85 | US10231967, Example 85 | US9918985...)
Affinity DataIC50: 0.800nMAssay Description:SH-SY5Y cells were cultured in DMEM/F-12 with Glutamax, 10% FCS and 1% non-essential amino acids and cryopreserved and stored at −140° C. at a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

Displayed 1 to 50 (of 2570 total ) | Next | Last >>
Jump to: